When in Duskwood, was infected with "Infected Bite" by spiders just south of the city of Darkshire...
Despite having mana shield active, and full mana up - this dot continued to leech health of me.
As I understand it, it's supposed to leech the absorbtion effect on the shields first, and not pass through the absorption effects on the character to leech the health, when there is still power on the shield, regardless of what kind of shield it is.
A quite serious bug, and if there are more of these venom type bugs, which bypass shields like this, it seriously needs to be fixed.